Basic Informat
ion
Teacher Name: Wenda Wu
Job Title: Associate Professor
Phone：025-84395227
Email：wuwenda@njau.edu.cn
Address：College of Veterinary Medicine,
Nanjing Agricultural University,
1 Weigang, Nanjing 210095, China
Research Areas and Descriptors：
Immunotoxicology
Mycotoxin and Food Safety
Small Animal Disease
Profile
DEGREE
Ph.D., Nanjing Agricultural University, 2012
PROFESSIONAL EXPERIENCES
Postdoctoral/Visiting Scholar, Department of Food Science and Human Nutrition, Michigan State University, 2010-2013, 2015-2016
PUBLICATIONS
[1] Kun Sheng, Hua Zhang, Jianming Yue, Wei Gu, Chao Gu, Haibin Zhang, Wenda Wu*. Anorectic response to the trichothecene T-2 toxin correspond to plasma elevations of the satiety hormone glucose-dependent insulinotropic polypeptide and peptide YY3-36. Toxicology, 2018, 402-403:28-36.
[2] Jie Zhang, Kun Sheng, Wenda Wu*, Haibin Zhang. Anorectic responses to T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol correspond to plasma elevations of neurotransmitters 5-hydroxytryptamine and substance P. Ecotoxicology and Environmental Safety, 2018, 161:451-458.
[3] Jie Zhang, Hua Zhang, Shengli Liu, Wenda Wu*, Haibin Zhang. Comparison of anorectic potencies of type A trichothecenes T-2 Toxin, HT-2 Toxin, diacetoxyscirpenol, and neosolaniol. Toxins, 2018, 10(5):179.
[4] Wenda Wu, Kun Sheng, Xinglian Xu, Haibin Zhang, Guanghong Zhou*. Potential roles for glucagon-like peptide-17-36 amide and cholecystokinin in anorectic response to the trichothecene mycotoxin T-2 toxin. Ecotoxicology and Environmental Safety, 2018, 153(30):181-187.
[5] Wenda Wu, Hui-Ren Zhou, James J. Pestka*. Potential roles for calcium-sensing receptor (CaSR) and transient receptor ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin). Archives of Toxicology, 2017, 91(1):495-507.
[6] Jie Zhang, Hui Jia, Qingqing Wang, Yajie Zhang, Wenda Wu*, Haibin Zhang. Role of peptide YY3-36 and glucose-dependent insulinotropic polypeptide in anorexia induction by trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxicological Sciences, 2017, 159(1):203-210.
[7] Jie Zhang, Shengli Liu, Hua Zhang, Yuanyuan Li, Wenda Wu*, Haibin Zhang. Gut satiety hormones cholecystokinin and glucagon-like Peptide-17-36 amide mediate anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol. Toxicology and Applied Pharmacology, 2017, 335:49-55.
[8] Wenda Wu, Hui-Ren Zhou, Steven J. Bursian, Jane E. Link, James J. Pestka*. Calcium-sensing receptor and transient receptor ankyrin-1 mediate emesis induction by deoxynivalenol (vomitoxin). Toxicological Sciences, 2017, 155(1):32-42.
[9] Hui Jia, Wenda Wu, Xi Lu, Jie Zhang, Chenghua He, Haibin Zhang*. Role of glucagon-like peptide-1 and gastric inhibitory peptide in anorexia induction following oral exposure to the trichothecene mycotoxin deoxynivalenol (vomitoxin). Toxicological Sciences, 2017, 159(1):16-
24.
[10] Wenda Wu, Hui-Ren Zhou, Steven J. Bursian, Jane E. Link, James J. Pestka*. Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations peptide YY3-36 and 5-hydroxytryptamine. Archives of Toxicology, 2016, 90(4):997-1007.
[11] Denis Male*, Wenda Wu(Co-first author), Nicole J. Mitchell, Steven J. Bursian, James J. Pestka, Felicia Wu. Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology. Food and Chemical Toxicology, 2016, 94:178-185.
[12] Dawei Liu, Hongyi Liu, Haibin Zhang, Mingchang Cao, Yong Sun, Wenda Wu*, Changhu Lu. Potential natural exposure of endangeredred-crowned crane (Grus japonensis) to mycotoxins aflatoxin B1, deoxynivalenol,zearalenone, T-2 toxin, and ochratoxin A. Journal of Zhejiang University-SCIENCE B, 2016, 17(2):158-168.
[13] Denis Male, Nicole J. Mitchell, Wenda Wu, Steven J. Bursian, James J. Pestka, Felicia Wu*. Modelling the anorectic potencies of food-borne trichothecenes by benchmark dose and incremental area under the curve methodology. World Mycotoxin Journal, 2016, 9(2):279-288.
[14] Xiumei zhao, Rongjia Li, Chuang Zhou, Jie Zhang, Chenghua He, Yating Zheng, Wenda Wu, Haibin Zhang*. Separation and purification of deoxynivalenol (DON) mycotoxin from wheat culture using a simple two-step silica gel column chromatography. Journal of Integrative Agriculture, 2016, 15(3):694-701.
[15] Wenda Wu, Hui-Ren Zhou, Xiao Pan, James J. Pestka*. Comparison of anorectic potencies of the trichothecenes T-2 toxin, HT-2 toxin and satratoxin G to the ipecac alkaloid emetine. Toxicology Reports, 2015, 2:238-251.
[16] Zhiyu Shi, Yating Zheng, Haobo Zhang, Chenghua He, Wenda Wu, Haibin Zhang*. DNA electrochemical aptasensor for detecting fumonisins B1 based on graphene and thionine nanocomposite. Electroanalysis, 2015, 27(5):1097-1103.
[17] Wenda Wu, Hui-Ren Zhou, Steven J. Bursian, Xiao Pan, Jane E.Link, Franz Berthiller, Gerhard Adam, Anthony Krantis, Tony Durst, James J. Pestka*. Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-
glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544. Toxicological Sciences, 2014, 142(1):167-181.
[18] Wenda Wu, Hui-Ren Zhou, Kaiyu He, Xiao Pan, Yoshiko Sugita-Konishi, Maiko Watanabe, Haibin Zhang, James J. Pestka*. Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol,
3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicological Sciences, 2014, 138(2):278-
289.
[19] Wenda Wu, Kaiyu He, Hui-Ren Zhou, Franz Berthiller, Gerhard Adam, Yoshiko Sugita-Konishi, Maiko Watanabe, Anthony Krantis, Tony Durst, Haibin Zhang, James J. Pestka*. Effects of oral exposure to naturally-occurring and synthetic deoxynivalenol congeners on proinflammatory cytokine and chemokine mRNA expression in the mouse. Toxicology and Applied Pharmacology, 2014, 278(2):107-115.
[20] Wenda Wu, Haibin Zhang*. Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse. Journal of Toxicological Sciences, 2014, 39(6):875-886.
[21] Yuwei Wang, Wenda Wu(Co-first author), Xichun Wang, Chenghua He, Hua Yue, Zhe Ren, Haibin Zhang*. Inhibitory effects of deoxynivalenol on gastric secretion in rats. Journal of Food Protection, 2014, 77(8):1367-1371.
[22] Wenda Wu, Melissa A. Bates, Steven J. Bursian, Brenna Flannery, Hui-Ren Zhou, Jane E. Link, Haibin Zhang, James J. Pestka*. Peptide YY3-36 and 5-hydroxytryptamine mediate emesis induction by the trichothecene deoxynivalenol (vomitoxin). Toxicological Sciences, 2013, 133(1):186-195.
[23] Wenda Wu, Melissa A. Bates, Steven J. Bursian, Jane E. Link, Brenna M. Flannery, Yoshiko Sugita-Konishi, Maiko Watanabe, Haibin Zhang, James J. Pestka*. Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicological Sciences, 2013, 131(1):279-291.
[24] Wenda Wu, Brenna M. Flannery, Yoshiko Sugita-Konishi, Maiko Watanabe, Haibin Zhang, James J. Pestka*. Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol. Food and Chemical Toxicology, 2012, 50(6):2056-2061.
[25] Brenna M. Flannery, Wenda Wu, James J. Pestka. Characterization of deoxynivalenol- induced anorexia using mouse bioassay. Food and Chemical Toxicology, 2011, 49(8):1863-
1869.
TEACHING
Veterinary Internal Medicine
Veterinary Clinical Diagnosis
Special Topics in Small Animal Internal Medicine
ACADEMIC ASSOCITATION MEMBERSHIP
Chinese Association of Animal Science and Veterinary Medicine, Senior Member
Jiangsu Society of Toxicology, Executive Council Member
Chinese Society of Toxicology, Member
American Society of Toxicology, Member
AWARDS & HONORS
2017 Advanced Worker Awards
2016 Boehringer Ingelheim Awards for Teachers
2015 Zhongshan Academic Rookie of Nanjing Agricultural University
2014 Boehringer Ingelheim Awards for Teachers
2014 The Excellent Doctoral Dissertation of Jiangsu Province
2014 The Excellent Doctoral Dissertation of Nanjing Agricultural University
