Basic Information
Teacher Name: JIANG Ping
Job Title: Dean, Dr., Professor, DVM
Phone：86 25 84395504
Email：jiangp@njau.edu.cn
Research Areas and Descriptors：Diagnosis and immunology of animal infectious disease
Profile
Dean of College of Veterinary Medicine in Nanjing Agricultural University, Director of the Key Laboratory of animal bacteriology of the Ministry of Agriculture, China. He graduated in the college of veterinary medicine of Nanjing agricultural university in 1989. He studied as visiting scholar in Rush-Presbyterian-St. Luke’s Medical Center in Chicago of America during the period of 2000-2001, and in Ontario Veterinary College of University of Guelph in Canada in 1998. His research focuses on viral diseases of swine with special emphasis on porcine reproductive and respiratory syndrome virus,porcine circovirus type 2 associated diseases and pseudorabies, and on the mechanisms of immunity against these viruses. He has published more than 250 papers, including 82 papers in peer-reviewed international journals. He also has edited 5 books, including a Chinese textbook, Veterinary Biologicology. His research team has developed 3vaccines that has been wildly used for preventing and control swine diseases in China.
Education:
09/1994-01/1998: Doctor of Agriculture Science (PhD)
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Nanjing Agricultural University,
China
09/1986-06/1989: Master of Agriculture Science (PhD)
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Nanjing Agricultural University,
China
College of Veterinary Medicine, Nanjing Agricultural University,
China
Research and Professional Experience:
04/2002-current: Professor, Director, Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Nanjing Agricultural University, China.
02/2000-11/2001: Visiting scholar, Department of General Surgery, Rush-Presbyterian-St. Luke’s MedicalCenter, Chicago,
USA
02/1998-08/1998: Visiting scholar, Department of Pathobiology, Ontario Veterinary College, University of Guelph,
Canada
01/1997-03/2002: Associate professor,College of Veterinary Medicine, Nanjing Agricultural University,
China
.
05/1992-12/1996: Lecture,College of Veterinary Medicine, Nanjing Agricultural University,
China
.
06/1989-04/1992: Lecture assistant,College of Veterinary Medicine, Nanjing Agricultural University,
China
.
Awards:
1. An expert in the technology system in national pig industry, China
2. The team was awarded in 2012 as the outstanding talent and innovation team of China in agricultural research.
3. Youth Talents of Science and Technology of the “333” Project of Jiangsu Province, Chian
4. An Excellent Talent of the New Century Program of the Ministry of Education
The Main Publications:
1. Chen X, Bai J, Liu X, Song Z, Zhang Q, Wang X, Jiang P*., Nsp1α of PRRSV strain BB0907 impairs the function of monocyte-derived dendritic cells via the release of soluble CD83. J Virol. 2018 Jul 17;92(15). pii: e00366-18.
2. Dong J, Gu Z, Jin L, Lv L, Wang J, Sun T, Bai J, Sun H, Wang X, Jiang P*. Polymorphisms affecting the gE and gI proteins partly contribute to the virulence of a newly-emergent highly virulent Chinese pseudorabies virus. Virology. 2018 Apr 6;519:42-52.
3. Chen X, Zhang Q, Bai J, Zhao Y, Wang X, Wang H,JiangP*. The Nucleocapsid protein and nonstructural protein 10 of highly pathogenic porcine reproductive and respiratory syndrome virus enhance CD83 production via NF-κB and Sp1 signaling pathways. J Virol. 2017 Aug 24;91(18).pii: e00986-17.
4. Zhang Q, Bai J, Hou H, Song Z, Zhao Y,JiangP*. A novel recombinant porcine reproductive and respiratory syndrome virus with significant variation in cell adaption and pathogenicity. Vet Microbiol. 2017 Sep;208:150-158.
5. Song Z, Zhang Q, Liu X, Bai J, Zhao Y, Wang X, Jiang P*. Cholesterol 25-Hydroxylase is an Interferon-inducible Factor that Protects against Porcine Reproductive and Respiratory Syndrome Virus Infection. Vet Microbiol. 2017, 210:153-161.
6. Zhao H, Han Q, Zhang L, Zhang Z, Wu Y, Shen H,Jiang P*. Emergence of mosaic recombinant strains potentially associated with vaccine JXA1-R and predominant circulating strains of porcine reproductive and respiratory syndrome virus in different provinces of China. Virol J. 2017 Apr 4;14(1):67.
7. Wang H, Bai J, Fan B, Li Y, Zhang Q, Jiang P*. The Interferon-Induced Mx2 Inhibits PorcineReproductive and RespiratorySyndromeVirus Replication. J Interferon Cytokine Res. 2016 Feb;36(2):129-39.
8. Fang J, Wang H, Bai J, Zhang Q, Li Y, Liu F, Jiang P*.，Monkey viperin restricts porcinereproductive and respiratory syndrome virus replication. PLoS One. 2016 May 27;11(5):e0156513.
9. Fan B, Liu X, Bai J, Zhang T, Zhang Q, Jiang P*.Influence of the amino acid residues at 70 in M protein of porcinereproductive and respiratorysyndromevirus on viral neutralization susceptibility to the serum antibody. Virol J. 2016 Mar 22;13:51.
10. Zhu X, Bai J, Liu P, Wang X, Jiang P*.，Suppressor of cytokine signaling 3 plays an important role in porcine circovirus type 2 subclinical infection by down regulating proinflammatory responses. Sci Rep. 2016 Sep 1;6:32538.
11. Liu J, Zhang X, Ma C, You J, Dong M, Yun S,Jiang P*.，Heat shock protein 90 is essential for replication of porcine circovirus type 2 in PK-15 cells. Virus Res. 2016 Aug 20;224:29-37.
12. Leghari RA, Fan B, Wang H, Bai J, Zhang L, Abro SH, Jiang P*.，Full-length genome sequencing analysis of avian infectious bronchitis virus isolate associated with nephropathogenic infection. Poult Sci. 2016 Aug 26. pii: pew259.
13. Fan B, Zhang H, Bai J, Liu X, Li Y, Wang X, Jiang P*., Pathogenesis of highly pathogenic porcinereproductive and respiratorysyndromevirus in Chinese Tibetan swine. Res Vet Sci. 2016 Oct;108:33-7.
14. Fan B, Liu X, Bai J, Zhang T, Zhang Q, Jiang P*. The amino acid residues at 102 and 104 in GP5 of porcine reproductive and respiratory syndrome virus regulate viral neutralization susceptibility to the porcine serum neutralizing antibody.Virus Res. 2015 Apr 20;204:21-30.
15. Zhao PD, Tan C, Dong Y, Li Y, Shi X, Bai J, Jiang P*. Genetic variation analyses of porcine epidemic diarrhea virus isolated in mid-eastern China from 2011 to 2013. Can J Vet Res. 2015 Jan;79(1):8-15.
16. Liu X, Fan B, Bai J, Wang H, Li Y, Jiang P*. The N-N non-covalent domain of the nucleocapsid protein of type 2 porcine reproductive and respiratory syndrome virus enhances induction of IL-10 expression. J Gen Virol. 2015 Jan 22.
17. Bai J, Chen X, Jiang K, Zeshan B, Jiang P*. Identification of VP1 peptides diagnostic of encephalomyocarditis virus from swine. Virol J. 2014 Dec 30;11(1):226.
18. Fang P, Bai J, Liu X, Dong J, Sun T, Jiang P*. Construction and characterization of an infectious cDNA clone of encephalomyocarditis virus from pigs in China. Arch Virol. 2015 Mar; 160(3): 805-9.
19. Gu Z, Dong J, Wang J, Hou C, Sun H, Yang W, Bai J, Jiang P*. A novel inactivated gE/gI deleted pseudorabies virus (PRV) vaccine completely protects pigs from an emerged variant PRV challenge. Virus Res. 2015 Jan 2; 195:57-63.
20. Liu J, Bai J, Zhang L, Hou C, Li Y, Jiang P*. Proteomic alteration of PK-15 cells after infection by porcine circovirus type 2. Virus Genes. 2014 Dec;49(3):400-16.
21. Zhao PD, Bai J, Jiang P, Tang TS, Li Y, Tan C, Shi X. Development of a multiplex TaqMan probe-based real-time PCR for discrimination of variant and classical porcine epidemic diarrhea virus. J Virol Methods. 2014 Sep;206:150-5.
22. Liu J, Zhang L, Zhu X, Bai J, Wang L, Wang X, Jiang P*. Heat shock protein 27 is involved in PCV2 infection in PK-15 cells. Virus Res. 2014 Aug 30;189:235-42.
23. Liu X, Li Y, Lu Q, Bai J, Wang X, Jiang P*. A new porcine reproductive and respiratory syndrome virus strain with highly conserved molecular characteristics in its parental and attenuated strains. Virus Genes. 2014 Oct;49(2):259-68.
24. Fan B, Wang H, Bai J, Zhang L, Jiang P*. A novel isolate with deletion in GP3 gene of porcine reproductive and respiratory syndrome virus from mid-eastern China. Biomed Res Int. 2014; 2014:306130.
25. Liu J, Bai J, Zhang L, Jiang Z, Wang X, Li Y, Jiang P*. Hsp70 positively regulates porcine circovirus type 2 replication in vitro. Virology. 2013 Dec;447(1-2):52-62.
26. Li Y, Kwok AH, Jiang J, Zou Y, Zheng F, Chen P, Hou C, Leung FC, Jiang P*. Complete genome analysis of a Haemophilusparasuisserovar 12 strain from China. PLoS One. 2013 Sep 2;8(9):e68350.
27. Zhang L, Liu J, Bai J, Du Y, Wang X, Liu X, Jiang P*. Poly(I:C) inhibits porcine reproductive and respiratory syndrome virus replication in MARC-145 cells via activation of IFIT3. Antiviral Res. 2013 Sep;99(3):197-206.
28. Zhou Y, Bai J, Li Y, Wang X, Wang X, Jiang P*. Suppression of immune responses in pigs by nonstructural protein 1 of porcine reproductive and respiratory syndrome virus. Can J Vet Res. 2012 Oct;76(4):255-60.
29. Zhang L, Bai J, Liu J, Wang X, Li Y, Jiang P*. Toll-like receptor ligands enhance the protective effects of vaccination against porcine reproductive and respiratory syndrome virus in swine. Vet Microbiol. 2013 Jun 28;164(3-4):253-60.
30. Hua T, Wang X, Bai J, Zhang L, Liu J, Jiang P*. Attenuation of porcine circovirus type-2b by replacement with the Rep gene of porcine circovirus type-1. Virus Res. 2013 May;173(2):270-9.
31. Li W, Wang X, Bai J, Ma T, Li Z, Li Y, Jiang P. Construction and immunogenicity of recombinant porcine circovirus-like particles displaying somatostatin. Vet Microbiol. 2013 Apr 12; 163(1-2):23-32.
32. Liu J, Bai J, Lu Q, Zhang L, Jiang Z, Michal JJ, He Q, Jiang P*. Two-dimensional liquid chromatography-tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling approach revealed first proteome profiles of pulmonary alveolar macrophages infected with porcine circovirus type 2. J Proteomics. 2013 Feb 21; 79:72-86.
33. Bai J, Jiang K, Zhang G, Wang X, Li Y, Jiang P*. Pathogenicity and molecular analysis of an encephalomyocarditis virus isolate from mideastern China. Can J Vet Res. 2012 Apr;76(2):157-60.
34. Wang X, Bai J, Zhang L, Wang X, Li Y, Jiang P*. Poly(A)-binding protein interacts with the nucleocapsid protein of porcine reproductive and respiratory syndrome virus and participates in viral replication. Antiviral Res. 2012 Dec;96(3):315-23.
35. Bai J, Jiang K, Zhang L, Wang X, Wang X, Li Y, Jiang P*. Protective efficacy of adenovirus-mediated small interfering RNAs against encephalomyocarditis virus challenge in mice. J Virol Methods. 2012 Nov;185(2):204-12.
36. Lu Q, Bai J, Zhang L, Liu J, Jiang Z, Michal JJ, He Q, Jiang P*. Two-dimensional liquid chromatography-tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling approach revealed first proteome profiles of pulmonary alveolar macrophages infected with porcine reproductive and respiratory syndrome virus. J Proteome Res. 2012 May 4;11(5):2890-903.
37. Li Y, Huang J, Jia Y, Du Y, Jiang P*, Zhang R. Genetic characterization of Aleutian mink disease viruses isolated in China. Virus Genes. 2012 Aug;45(1):24-30.
38. Bai J, Jiang K, Zeshan B, Wang X, Li Y, Jiang P*. Inhibition of encephalomyocarditis virus replication by shRNA targeting 1D and 3AB genes in vitro and in vivo. Virus Genes. 2012 Apr;44(2):183-90.
39. Song Y, Zhou Y, Li Y, Wang X, Bai J, Cao J, Jiang P*. Identification of B-cell epitopes in the NSP1 protein of porcine reproductive and respiratory syndrome virus. Vet Microbiol. 2012 Mar 23;155(2-4):220-9.
40. Li P, Bai J, Li JX, Zhang GL, Song YH, Li YF, Wang XW, Jiang P*. Molecular cloning, sequencing, and expression of the outer membrane protein P2 gene of Haemophilus parasuis. Res Vet Sci. 2012 Oct;93(2):736-42.
41. Cao J, Wang X, Du Y, Li Y, Wang X, Jiang P*. CD40 ligand expressed in adenovirus can improve the immunogenicity of the GP3 and GP5 of porcine reproductive and respiratory syndrome virus in swine. Vaccine. 2010 Nov 3;28(47):7514-22.
42. Zeshan B, Mushtaq MH, Wang X, Li W, Jiang P*. Protective immune responses induced by in ovo immunization with recombinant adenoviruses expressing spike (S1) glycoprotein of infectious bronchitis virus fused/co-administered with granulocyte-macrophage colony stimulating factor. Vet Microbiol. 2011 Feb 24; 148(1):8-17.
43. Li W, Wang X, Ma T, Feng Z, Li Y, Jiang P*. Genetic analysis of porcine circovirus type 2 (PCV2) strains isolated between 2001 and 2009: genotype PCV2b predominate in postweaningmultisystemic wasting syndrome occurrences in eastern China. Virus Genes. 2010 Apr;40(2):244-51.
44. Li JX, Jiang P*, Wang Y, Li YF, Chen W, Wang XW, Li P. Genotyping of Haemophilus parasuis from diseased pigs in China and prevalence of two coexisting virus pathogens.Prev Vet Med. 2009 Oct 1;91(2-4):274-9.
45. Wang X, Li J, Jiang P*, Li Y, Zeshan B, Cao J, Wang X. GM-CSF fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus increased the immune responses and protective efficacy against virulent PRRSV challenge. Virus Res. 2009 Jul;143(1):24-32.
46. Li Y, Wang X, Jiang P*, Wang X, Chen W, Wang X, Wang K. Genetic variation analysis of porcine reproductive and respiratory syndrome virus isolated in China from 2002 to 2007 based on ORF5. Vet Microbiol. 2009 Jul 2;138(1-2):150-5.
47. Li J, Jiang P*, Li Y, Wang X, Cao J, Wang X, Zeshan B. HSP70 fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus enhanced the immune responses and protective efficacy against virulent PRRSV challenge in pigs. Vaccine. 2009 Feb 5;27(6):825-32.
48. Li Y, Wang X, Jiang P*, Chen W, Wang X. Genetic analysis of two porcine reproductive and respiratory syndrome viruses with different virulence isolated in China. Arch Virol. 2008;153(10):1877-84.
49. Jiang W, Jiang P*, Wang X, Li Y, Du Y, Wang X. Enhanced immune responses of mice inoculated recombinant adenoviruses expressing GP5 by fusion with GP3 and/or GP4 of PRRS virus. Virus Res. 2008 Sep; 136(1-2):50-7.
50. Feng Z, Jiang P*, Wang X, Li Y, Jiang W. Adenovirus-mediated shRNA interference against porcine circovirus type 2 replication both in vitro and in vivo. Antiviral Res. 2008 Mar; 77(3):186-94.
51. Li Y, Wang X, Bo K, Wang X, Tang B, Yang B, Jiang W, Jiang P*. Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China. Vet J. 2007 Nov;174(3):577-84.
52. Jiang W, Jiang P*, Wang X, Li Y, Wang X, Du Y. Influence of porcine reproductive and respiratory syndrome virus GP5 glycoprotein N-linked glycans on immune responses in mice. Virus Genes. 2007 Dec;35(3):663-71.
53. Jiang W, Jiang P*, Li Y, Wang X, Du Y. Analysis of immunogenicity of minor envelope protein GP3 of porcine reproductive and respiratory syndrome virus in mice. Virus Genes. 2007 Dec; 35(3):695-704.
54. Wang X, Jiang P*, Li Y, Jiang W, Dong X. Protection of pigs against post-weaning multisystemic wasting syndrome by a recombinant adenovirus expressing the capsid protein of porcine circovirus type 2. Vet Microbiol. 2007 Apr 15;121(3-4):215-24.
55. Jiang W, Jiang P*, Li Y, Tang J, Wang X, Ma S. Recombinant adenovirus expressing GP5 and M fusion proteins of porcine reproductive and respiratory syndrome virus induce both humoral and cell-mediated immune responses in mice. Vet ImmunolImmunopathol. 2006 Sep 15;113(1-2):169-80.
56. Jiang P*, Chen PY, Dong YY, Cai JL, Cai BX, Jiang ZH. Isolation and genome characterization of porcine reproductive and respiratory syndrome virus in P.R. China. J Vet Diagn Invest. 2000 Mar;12(2):156-8.
57. Jiang P, Ojkic D, Tuboly T, Huber P, Nagy E. Application of the polymerase chain reaction to detect fowl adenoviruses. Can J Vet Res. 1999 Apr;63(2):124-8.
58. Jiang P, Kumar A, Parrillo JE, Dempsey LA, Platt JL, Prinz RA, Xu X. Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity. J Biol Chem. 2002 Mar 15;277(11):8989-98.
